Stem Cell Institute of New Jersey

About the Institute

Joseph R. Bertino, M.D.

University Professor of Medicine and Pharmacology
Interim Director, Stem Cell Institute of New Jersey
Interim Director, The Cancer Institute of New Jersey
UMDNJ-Robert Wood Johnson Medical School

Joseph R. Bertino, MD, is University Professor of medicine and pharmacology, UMDNJ-Robert Wood Johnson Medical School and is the interim director of the school's Cancer Institute of New Jersey Bertino in New Brunswick. He was named interim director of the Stem Cell Institute of New Jersey in 2007. He has been an American Cancer Society professor since 1976. Dr. Bertino joined The Cancer Institute of New Jersey in 2002 as associate director and was appointed chief scientific officer in 2004.

Prior to joining The Cancer Institute of New Jersey at Robert Wood Johnson Medical School, Dr. Bertino served as chair of the Molecular Pharmacology and Therapeutics Program, and member and co-head of the Program in Developmental Therapy and Clinical Investigation at Memorial Sloan-Kettering Institute for Cancer Research. From 1973 to 1986, Dr. Bertino served as director of the Yale Comprehensive Cancer Center, including director of the center and associate director for clinical research. Dr. Bertino has been internationally recognized for his role in finding curative treatments for leukemia and lymphoma.

During his academic career, Dr.Bertino has received several awards and honors for his research accomplishments, including the Rosenthal Award from the American Association of Clinical Research, the Karnofsky Award from the American Society for Clinical Oncology, and the American Cancer Society Medal of Honor. He was the founding editor of the Journal of Clinical Oncology. Currently, he is the associate editor for Cancer Research and Clinical Cancer Research and also the editor of the Encyclopedia of Cancer. Dr. Bertino served as president for the American Society of Clinical Oncology in 1976, and president of the American Association for Cancer Research in 1995-96.

Dr. Bertino is the author and co-author of more than 400 scientific publications. His research elucidated the mechanisms of methotrexate resistance in experimental models, and in cancer patients, has helped shape optimal methotrexate administration schedules. This has provided a foundation for rational design and development of anticancer agents. His laboratory is studying the relationship between tumor suppressor gene abnormalities and drug resistance, and the use of drug resistant genes to protect bone marrow from chemotherapy toxicity. In addition to this gene therapy research, Dr. Bertino’s lab also is focusing on umbilical cord blood expansion in stem cell research.