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Millonig, James Ph.D.
Photograph of James Millonig, PhD

Associate Professor
PhD, Princeton University, 1994

Phone: (848) 445-9852

: (732) 235-4850


Research Interests:
 Neurodevelopmental disorders, Autism Spectrum Disorder, neural tube defects, schizophrenia

Selected Publications
: For complete list PubMed

Gharani N, Benayed R, Mancuso V, Brzustowicz LM and Millonig JH. (2004) Association of the homeodomain transcription factor, ENGRAILED 2, with Autism Spectrum Disorder. Mol. Psychiatry 9: 474-484.

Benayed R, Gharani N, Rossman I, Mancuso V, Lazar G, Kamdar S, Bruse SE, Tischfield S, Smith BJ, Zimmerman R, DiCicco-Bloom E, Brzustowicz LM, Millonig JH. (2005) Support for the homeobox transcription factor, ENGRAILED 2, as an Autism Spectrum Disorder (ASD) susceptibility locus. Am J of Hum Genetics 77: 851-868.

Matteson PG, Desai J, Korstanje R, Lazar G, Borsuk TE, Rollins J, Kadambi S, Joseph J, Rahman T, Wink J, Benayed R, Paigen B, Millonig JH (2008) The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development PNAS 105: 2088-2093.

Korstanje R, Desai J, Lazar G, King B, Rollins J, Spurr M, Joseph J, Kadambi S, Li Y, Cherry A, Matteson PG, Paigen B, Millonig JH (2008) Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects. Physiol Genomics 35: 296-304.

Wratten NS, Memoli H, Huang Y, Azaro MA, Messenger J, Matteson PG, Dulencin A, Hayter JE, Chow EW, Bassett AS, Buyske S, Millonig JH, Vieland VJ, Brzustowicz LM. (2009) Identification of a functional noncoding variant in NOS1AP associated with schizophrenia and increased gene expression Am J Psychiatry 166:434-41.

Benayed R, Choi J, Matteson PG, Gharani N, Kamdar S, Brzustowicz LM, Millonig JH. (2009) Autism Associated Haplotype Affects the Regulation of the Homeobox Gene, ENGRAILED 2. Biol Psychiatry 60: 911-17.

Hadzimichalis NM, Previtera ML, Moreau MP, Li B, Dulencin A, Matteson PG, Millonig JH, Brzustowicz LB, Firestein BL. (2010). NOS1AP protein levels are altered in BA46 and cerebellum of patients with schizophrenia. Schizophr Res 124:248-50.

Deng Q, Andersson E, Hedlund E, Alekseenko Z, Coppola E, Panman L, Millonig JH, Brunet J-F, Ericson J. (2011) Specific and Integrated Roles of Lmx1a, Lmx1b and Phox2a in Ventral Midbrain Development. Development 138:3399-40.

Choi J, Kamdar S, Rahman T, Matteson PG, Millonig JH. (2011) ENGRAILED 2 (EN2) genetic and functional analysis. Autism Spectrum Disorders - From Genes to Environment, ISBN 978-953-307-558-7, edited by Tim Williams. pp1-22.

Choi J, Ababon MR, MattesonPG, Millonig JH. (2012) Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function. Human Molecular Genetics 21, 1566-80.

Anderson S, Botti C, Li B, Millonig JH, Lyon E, Millson A, Karabin SSM, Sklower Brooks S, Medium Chain Acyl-CoA Dehydrogenase Deficiency Detected Among Hispanics by New Jersey Newborn Screening (2012) American Journal of Medical Genetics, in press.

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