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Message from the Chief
Welcome!
 The Division of Developmental Medicine and Research was founded to serve
the vital function of fostering interactions between basic and clinical
research programs, thereby fostering translational research.
We have targeted three key areas for development, each of which focuses
on animal models of human disease. Growth in these areas effectively synergizes
with ongoing research at RWJMS and complements initiatives in vertebrate
developmental biology at the Child Health Institute of New Jersey and
in functional genomics and proteomics at the Cancer Institute of New Jersey.
- Mouse models of human disease: Due to the advent
of transgenic technologies, mouse models have become vitally important
for studying the molecular basis and pathogenesis of human diseases.
The generation of such models will provide many additional avenues for
fostering interactions with the clinical community.
- Small animal imaging: Non-invasive techniques that
allow inspection of tumors or other malformations in live animals are
necessary to monitor the consequences of various treatment options.
Small animal imaging will be vital for such translational applications
as well as vertebrate development studies that will be ongoing in the
Child Health Institute of New Jersey.
- Using mouse models for pre-clinical testing: Valid
mouse models of human disease provide a unique opportunity for testing
therapeutic approaches prior to initiating such studies in human patients.
Using mouse models for such purposes will provide an ideal means of
fostering translational research as well as real opportunities for bringing
the bench to the clinic.
Thank you for your interest in our work.
Cory Abate-Shen, PhD
Chief, Division of Developmental Medicine and Research
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