Rothenbacher, F. P., Suzuki, M., Hurley, J. M., Montville, T. J., Kirn, T. J., Ouyang, M. and Woychik, N. A.
Clostridium difficile MazF toxin exhibits selective, not global, mRNA cleavage
J. Bact. 13, 3464-74 (2012) -Abstract-
Sharp J. D., Cruz J. W., Raman S., Inouye M., Husson R. N., Woychik N. A.
Growth and translation inhibition through sequence specific RNA binding by a Mycobacterium tuberculosis VapC toxin
J. Biol. Chem. 287, 12835-47 (2012) -Abstract-
Hurley, J. M., Cruz, J. W., Ouyang, M. and Woychik, N. A.
Bacterial toxin RelE mediates frequent codon-independent mRNA cleavage from the 5′ end of coding regions in vivo
J. Biol. Chem.
286, 14770-14778 (2011) -Abstract-
Zhu, L., Sharp, J. D., Kobayashi, H., Woychik, N. A., Inouye, M.
Noncognate Mycobacterium tuberculosis toxin-antitoxins can physically and functionally interact
J. Biol. Chem. 285, 39732-8 (2010) -Abstract-
Arbing, M. A., Handelman, S. K., Kuzin, A. P., Verdon, G., Wang, C., Su, M., Rothenbacher, F. P., Abashidze, M., Liu, M., Hurley, J. M., Xiao, R., Acton, T., Inouye, M., Montelione, G. T., Woychik, N. A. and Hunt, J.F.
Crystal structures of Phd-Doc, HigA, and YeeU establish multiple evolutionary links between microbial growth-regulating toxin and antitoxin (TA) systems
Structure 18, 996-1010 (2010) -Abstract-
Hurley, J. M. and Woychik, N. A.
Bacterial toxin HigB associates with ribosomes and mediates translation-dependent mRNA cleavage at A-rich sites.
J. Biol. Chem. 284, 18605-13 (2009) -Abstract-
Prysak, M. H., Mozdzierz, C. J., Cook, A. M., Zhu, L., Zhang, Y., Inouye, M. and Woychik, N. A.
Bacterial toxin YafQ is an endoribonuclease that associates with the ribosome and blocks translation elongation through sequence-specific and frame-dependent mRNA cleavage.
Mol. Microbiol. 71, 1071-87 (2009) -Abstract-
Liu, M., Zhang, Y., Inouye, M. and Woychik, N. A.
Bacterial Addiction Module Toxin Doc Inhibits Translation Elongation through its Association with the 30S Ribosome.
Proc. Natl. Acad. Sci. USA 105, 5885-5890 (2008) -Abstract-
Suzuki, M., Roy, R., Zheng, H., Woychik, N. A. and Inouye, M.
Text
J. Biol. Chem 281, 37559-37565 (2006) -Abstract-
Suzuki, M., Zhang, J., Liu, M., Woychik, N. A. and Inouye, M.
Single Protein Production in Living Cells Facilitated by an mRNA Interferase
Mol. Cell 16, 253-261 (2005) -Abstract-
(highlighted in The Scientist, Chemical Engineering News and Genetic Engineering News)
Tan, Q., Prysak, M. H. and Woychik, N. A.
Loss of the Rpb4/Rpb7 subcomplex in a mutant form of the Rpb6 subunit shared by RNA polymerases I, II and III.
Mol. Cell. Biol. 9, 3329-3338 (2003) -Abstract-
Woychik, N. A.
RNA polymerases and the eukaryotic transcription machinery
Encyclopedia of the Human Genome, Nature Publishing Group, London
(2003) online textbook at www.ehgonline.net
Woychik N. A., Hampsey M.
The RNA polymerase II machinery: structure illuminates function.
Cell 108, 453-463 (2002) -Abstract-
Miyao T., Barnett J. D. and Woychik N. A.
Deletion of the RNA polymerase subunit RPB4 acts as a global, not stress-specific, shut-off switch for RNA polymerase II transcription at high temperatures.
J. Biol. Chem. 276, 46408-46413 (2001) -Abstract-
Woychik, N. A. and Reinberg, D.
RNA polymerases: subunits and functional domains.
Encyclopedia of Life Sciences, Nature Publishing Group, London
(2002) online textbook at www.els.net
Tan, Q., Li, X., Sadhale, P. P., Miyao, T. and Woychik, N. A.
Multiple mechanisms of suppression circumvent transcription defects in an RNA polymerase mutant.
Mol. Cell. Biol. 20, 8124-8133 (2000) -Abstract-
Woychik, N. A.
TA-TAAA!! Transcription unveiled.
Trends Biochem. Sci. 25, 404 (2000)
Tan, Q., Linask, K. L., Ebright, R. H. and Woychik, N. A.
Activation mutants in yeast RNA polymerase II subunit RPB3 provide evidence for a structurally conserved surface required for activation in eukaryotes and bacteria.
Genes Dev. 14, 339-348 (2000) -Abstract-
Miyao, T. and Woychik, N. A.
RNA polymerase subunit RPB5 plays a role in transcriptional activation.
Proc. Natl. Acad. Sci. 95, 15281-15286 (1998) -Abstract-
Woychik, N. A.
Fractions to functions: RNA polymerase thirty years later.
Cold Spring Harbor Symp. Quant. Biol. Volume LXIII, 311-317 (1998) -Abstract-
McKune, K., Moore, P., Hull, M. W. and Woychik, N. A.
Six human RNA polymerase subunits functionally substitute for their yeast counterparts in vivo.
Mol. Cell. Biol.
15, 6895-6900 (1995) -Abstract-
Khazak, V., Sadhale, P. P., Woychik, N. A., Brent, R. and Golemis, E. A.
Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology.
Mol. Biol. Cell 6, 759-775 (1995) -Abstract-
Hull, M. W., McKune, K. and Woychik, N. A.
RNA polymerase subunit RPB9 is required for accurate start site selection.
Genes Dev. 9, 481-490 (1995) -Abstract-
Sadhale, P. P. and Woychik, N. A.
C25, an essential RNA polymerase III subunit related to the RNA polymerase II subunit RPB7.
Mol. Cell. Biol. 14, 4155-4159 (1994) -Abstract-
McKune, K. and Woychik, N. A.
Halobacterium S9 operon contains two genes encoding proteins homologous to subunits shared by eukaryotic RNA polymerases I, II, and III.
J. Bacteriol. 176, 4754-4756 (1994) -Abstract-
McKune, K. and Woychik, N. A.
Functional substitution of an essential yeast RNA polymerase subunit by its highly conserved mammalian counterpart.
Mol. Cell. Biol. 14, 4155-4159 (1994) -Abstract-
Woychik, N. A.
Regulating the regulators.
Trends Biochem. Sci. 19, 99-142 (1994) -Abstract-
Woychik, N. A., and Young, R. A.
Exploration of RNA polymerase II structure and function.
in: Transcription (R. Conaway and J. Conaway, eds.) Raven Press, New York, 227-242, (1994)
McKune, K., Richards, K. L., Edwards, A. M., Young, R. A. and Woychik, N. A.
RPB7, one of two dissociable subunits of RNA polymerase II, is essential for yeast cell viability.
Yeast, 9, 295-299 (1993) -Abstract-
Woychik, N. A., McKune, K., Lane, W. S. and Young, R. A.
RPB11, an essential yeast RNA polymerase II subunit is closely related to a yeast subunit common to RNA polymerase I and III.
Gene Expression, 3, 77-82 (1993) -Abstract-
Woychik, N. A. and Young, R. A.
Genes encoding TFIIIA and the RNA polymerase common subunit RPB6 are divergently transcribed in Saccharomyces cerevisiae.
Proc. Natl. Acad. Sci.
U.S.A. 89, 3999-4003 (1992) -Abstract-
Woychik, N. A., Lane, W. S. and Young, R. A.
Yeast RNA polymerase II subunit RPB9 is essential for growth at temperature extremes.
J. Biol. Chem. 266, 19053-19055 (1991) -Abstract-
Woychik, N. A. and Young, R. A.
RNA polymerase II subunit RPB10 is essential for yeast cell viability.
J. Biol. Chem. 265, 17816-17819 (1990) -Abstract-
Woychik, N. A. and Young, R. A.
RNA polymerase II structure and function.
Trends Biochem. Sci. 15, 347-351 (1990) -Abstract-
Kolodziej, P. A., Woychik, N., Liao, S.- M., and Young, R. A.
RNA polymerase II subunit composition, stoichiometry, and phosphorylation.
Mol. Cell. Biol. 10, 1915-1920 (1990) -Abstract-
Woychik, N. A., Liao, S-. M., Kolodziej, P. K., and Young, R. A.
Subunits shared by eukaryotic nuclear RNA polymerases.
Genes Dev. 4, 313-323 (1990) -Abstract-
Woychik, N. A. and Young, R. A.
RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth.
Mol. Cell. Biol. 9, 2854-2859 (1989) -Abstract-