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News and Events

Upcoming Events:

Graduate Student Research Seminar:
Thursday, February 19, 2015 @ 4:00 pm, in the RWJMS - Room V10.


Rutgers RWJMS Basic Science Seminar Series:
Thursday, February 26, 2015 @12 noon, in the RWJMS – Room V10.

Michael Verzi, Ph.D.  Assistant Professor, Rutgers University, Department of Genetics, Human Genetics Institute of New Jersey Member, Rutgers Cancer Institute of New Jersey, will be presenting. 
The title for seminar:  Epigenomics of Intestinal Disease.


Recent Publications:

Polyester monomers lack ability to bind and activate both androgenic and estrogenic receptors as determined by In Vitro and In Silico methods.Osimitz TG, Welsh WJ, Ai N, Toole C.Food Chem Toxicol. 2015 Jan;75:128-38. Epub 2014 Oct 28.

 

Novel virtual screening approach for the discovery of human tyrosinase inhibitors. Ai N, Welsh WJ, Santhanam U, Hu H, Lyga J.  PLoS One. 2014 Nov 26;9(11):e112788. eCollection 2014

 

Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice.Tao H, Zhang Y, Zeng X, Shulman GI, Jin S.  Nature Mediciene; 2014 Nov;20(11):1263-9. doi: 10.1038/nm.3699. Epub 2014 Oct 5.


mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.
Faller WJ, Jackson TJ, Knight JR, Ridgway RA, Jamieson T, Karim SA, Jones C, Radulescu S, Huels DJ, Myant KB, Dudek KM, Casey HA, Scopelliti A, Cordero JB, Vidal M, Pende M, Ryazanov AG, Sonenberg N, Meyuhas O, Hall MN, Bushell M, Willis AE, Sansom OJ.  Nature. 2014 Nov 5. doi: 10.1038/nature13896. [Epub ahead of print]

 

Rab1 is an mTORC1 activator and a colorectal oncogene.  Thomas JD*, Zhang, YJ*, Wei, YH, Cho JH, Wang HY and Zheng, X.F. Cancer Cell 2014; 26, 754–769 (*co-first authors) Featured in Preview by Cancer Cell 26, 601–602; Research Watch by Cancer Discovery, November 10, 2014


Identification of a Mg2+-sensitive ORF in the 5'-leader of TRPM7 magnesium channel mRNA. Nikonorova IA, Kornakov NV, Dmitriev SE, Vassilenko KS, Ryazanov AG. Nucleic Acids Res. 2014 Oct 17. pii: gku951.

Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice.  Tao H, Zhang Y, Zeng X, Shulman GI, Jin S.  Nat Med. 2014 Oct 5. doi: 10.1038/nm.3699. [

Please see also article which was published in Rutgers Today: http://news.rutgers.edu/research-news/attacking-type-2-diabetes-new-direction-encouraging-results/20141005#.VDVDaKhdXjE


Recent Research Grants and Awards:

Kiran Madura, PhD, professor of pharmacology, a four-year, $1,203,916 grant from the NIH
(1R01GM104968-01) for “A Role for Protein Degradation in Nucleotide Excision-Repair.”

Monica J. Roth, PhD, professor of pharmacology, a four-year, $1,172,331 grant from the NIH
(1R01GM108487-01) for “MuLV p12 Function in Tethering and Integration.”