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News and Events

Upcoming Events:

Graduate Student Research Seminar:
Thursday, December 18, 2014 @ 4:00 pm, in the RWJMS - Room V10.


Rutgers RWJMS Basic Science Seminar Series:
Thursday, January 08, 2015 @12 noon, in the RWJMS – Room V10.
Marion Gordon, PhD, Associate Professor, Fellow, American Association of Anatomists, Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, will be presenting. 
The title for seminar: TBA


Recent Publications:
mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.
Faller WJ, Jackson TJ, Knight JR, Ridgway RA, Jamieson T, Karim SA, Jones C, Radulescu S, Huels DJ, Myant KB, Dudek KM, Casey HA, Scopelliti A, Cordero JB, Vidal M, Pende M, Ryazanov AG, Sonenberg N, Meyuhas O, Hall MN, Bushell M, Willis AE, Sansom OJ.  Nature. 2014 Nov 5. doi: 10.1038/nature13896. [Epub ahead of print]

Rab1 is an mTORC1 activator and a colorectal oncogene.  Thomas JD*, Zhang, YJ*, Wei, YH, Cho JH, Wang HY and Zheng, X.F. Cancer Cell 2014; 26, 754–769 (*co-first authors) Featured in Preview by Cancer Cell 26, 601–602; Research Watch by Cancer Discovery, November 10, 2014


Identification of a Mg2+-sensitive ORF in the 5'-leader of TRPM7 magnesium channel mRNA.
Nikonorova IA, Kornakov NV, Dmitriev SE, Vassilenko KS, Ryazanov AG. Nucleic Acids Res. 2014 Oct 17. pii: gku951. [Epub ahead of print]

Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice. 
Tao H, Zhang Y, Zeng X, Shulman GI, Jin S.  Nat Med. 2014 Oct 5. doi: 10.1038/nm.3699. [Epub ahead of print]

Please see also article which was published in Rutgers Today: http://news.rutgers.edu/research-news/attacking-type-2-diabetes-new-direction-encouraging-results/20141005#.VDVDaKhdXjE

Degradation of Specific Nuclear Proteins Occurs in the Cytoplasm in Saccharomyces cerevisiae.
Chen L, Madura K. Genetics. 2014 Mar 12. [Epub ahead of print]

Please see link below, describing Dr. Madura’s recent publication:
http://www.yeastgenome.org/the-curious-case-of-the-proteasome-in-the-nucleus

Germline Quality Control: eEF2K Stands Guard to Eliminate Defective Oocytes.
Chu HP, Liao Y, Novak JS, Hu Z, Merkin JJ, Shymkiv Y, Braeckman BP, Dorovkov MV, Nguyen A, Clifford PM, Nagele RG, Harrison DE, Ellis RE, Ryazanov AG. Dev Cell. 2014 Mar 10;28(5):561-72. doi: 10.1016/j.devcel.2014.01.027. Epub 2014 Feb 27.

 

Recent Research Grants and Awards:

Kiran Madura, PhD, professor of pharmacology, a four-year, $1,203,916 grant from the NIH
(1R01GM104968-01) for “A Role for Protein Degradation in Nucleotide Excision-Repair.”

Monica J. Roth, PhD, professor of pharmacology, a four-year, $1,172,331 grant from the NIH
(1R01GM108487-01) for “MuLV p12 Function in Tethering and Integration.”