Michael Gallo,Ph.D.
Director, Toxicology Division: Director, NIEHS Center of Excellence
Professor
Robert Wood Johnson Medical School

Toxicology Division
Environmental and Occupational Health Sciences Institute

Research Interests:

Dioxins; Experimental Models; Pharmacology and Toxicology; Cytoplasmic Receptors; Hormones; Mechanisms of Carcinogenesis; Cell Surface Receptors; and Chemical Carcinogenesis.

Publications:

Gordon MK, Desantis A, Deshmukh M, Lacey CJ, Hahn RA, Beloni J, Anumolu SS, Schlager JJ, Gallo MA, Gerecke DR, Heindel ND, Svoboda KK, Babin MC, Sinko PJ. (2010)

Doxycycline hydrogels as a potential therapy for ocular vesicant injury. J Ocul Pharmacol Ther. 26(5):407-19.

Zarbl H, Gallo MA, Glick J, Yeung KY, Vouros P. (2010) The vanishing zero revisited: thresholds in the age of genomics. Chem Biol Interact; 184(1-2):273-278.

Dipaola RS, Gallo MA (2008). Hearsay medicine is not evidence-based medicine. Clin Cancer Res. 14(2):337-338.

Zhu BT, Gallo MA, Burger CW Jr, Meeker RJ, Cai MX, Xu S, Conney AH (2008). Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin administration and high-fat diet on the body weight and hepatic estrogen metabolism in female C3H/HeN mice. Toxicol Appl Pharmacol. 226(2):107-118.

Vijayanathan V, Greenfield NJ, Thomas TJ, Ivanova MM, Tyulmenkov VV, Klinge CM, Gallo MA, Thomas T. (2007) Effects of estradiol and 4-hydroxytamoxifen on the conformation, thermal stability, and DNA recognition of estrogen receptor beta. Biochem Cell Biol. 85(1):1-10.

Nair SK, Verma A, Thomas TJ, Chou TC, Gallo MA, Shirahata A, Thomas T. (2007) Synergistic apoptosis of MCF-7 breast cancer cells by 2-methoxyestradiol and bis(ethyl)norspermine. Cancer Lett. 250(2):311-322.

Vijayanathan V, Thomas TJ, Nair SK, Shirahata A, Gallo MA, Thomas T. (2006) Bending of the estrogen response element by polyamines and estrogen receptors alpha and beta: a fluorescence resonance energy transfer study. Int J Biochem Cell Biol. 38(7):1191-1206.

Gu X, Ke S, Liu D, Sheng T, Thomas PE, Rabson AB, Gallo MA, Xie W, Tian Y. (2006)

Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents. J Biol Chem. 281(26):17882-17889.

Lewis JS, Vijayanathan V, Thomas TJ, Pestell RG, Albanese C, Gallo MA, Thomas T. (2005) Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: a mechanism involving the p38 MAP kinase and phosphorylation of ATF-2. Oncol Res. 15(3):113-128.

Lewis JS, Thomas TJ, Pestell RG, Albanese C, Gallo MA, Thomas T. (2005) Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells. J Mol Endocrinol. 34:91-105.

Awards and Honors:

1985 UMDNJ Exceptional Merit Award

1979 Russell Sage College Outstanding Alumni